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User talk:TimVickers

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User talk:TimVickers/archive 1

[edit] Inquiry

Hi Tim. I hope I am asking you at a right place. Your page of structural alignment has a figure showing two PDB's aligned. Would you mind telling me how to achieve that? DALI and MaxSprout seem not sending me the desired result (e.g. a PDB file containing 2 or more records aligned, then say using Rasmol can displayed the result). Thanks a lot --Ross 18:27, 8 November 2006

[edit] Talk

Hi Tim. I'm a grad student at NYU working on malaria immunology. I'm thankful that you've taken up the torch on the big 3. I was just the other day reading the requirements for an FA and it seemed difficult to attain. But I'm guessing by your hard word, you've done it (I noticed the star up there in the corner of the page). I probably won't be as present as you; my attention waxes and wanes like the moon. But I'll be on more often now that I have set up an account. Good luck with the work! Kurtrik 00:39, 30 October 2006 (UTC)

[edit] Flu vaccine

I'll accept any solution you offer at Flu vaccine. WAS 4.250 01:16, 31 October 2006 (UTC)

I have no problem with that you try to reach a consensus. I also have no problems to see another version... as you can see I already tryed myself to post another version. My main point is to insert the study in some way into the article. greetings Ogno 02:11, 31 October 2006 (UTC)
My email has been set up now, so it should be possible for you to email me from my User page. Ogno 08:35, 31 October 2006 (UTC)
But to be honest you realy don't have to send me the pdf since I will have no time to read it anyway... I trust you that you will come forward with a good text for mentioning this study. Ogno 08:41, 31 October 2006 (UTC)

Bravo! Well done! I feel like I asked a friend for where to buy a dollar hotdog and was given a free three course top-quality meal. You're amazing. I woulda added "nonelderly" in front of "adult" in two places tho. Sometime in the future I might add something about nonhuman animal vaccine effectiveness and CDC conclusions on human flu vaccine efectiveness. Your choice of top notch sources is especially worthy of praise. Thanks. WAS 4.250 20:53, 31 October 2006 (UTC)

Superb! Thank you for that work... amazing! Ogno 09:32, 1 November 2006 (UTC)

[edit] Influenza

About:

"some authors have suggested that the Spanish influenza actually had a positive long-term effect on per-capita income growth, despite a large reduction in the working population and severe short-term depressive effects."

I remember reading about a study the US Government did decades ago on the effects of a nuclear war and part of its conclusion was that under many scenerios the NATO countries would see a reduction in population far greater than their reduction in material wealth leaving the average person still living more wealthy and not less wealthy. I don't remember when the study was done but I remember thinking the study was done before the issue of a nuclear winter was raised and when the USSR had fewer nukes than the US. Another thought: after the black death in Europe the remaining poor people were better off as there was greater competition for their wages (the poor died more proportionately). Some credit the higher cost of their wages with sparking increased mechanization and thus hastening the industrial revolution. So I read anyway. I guess the bottom line is if you only pay attention to survivors, many evils aren't. WAS 4.250 21:11, 31 October 2006 (UTC)

[edit] Cyclol

Hi Tim,

Wow, I just read the above message — do people even think that way? Ugh!

On a happier topic, I've been devoting myself recently to Cyclol, an early structural model of globular proteins. The article's not really relevant for modern biochemists, but it's an interesting topic, an early precursor of modern structural modeling. You may find it tiresome because the theory is so obviously wrong (from our modern perspective) but, I confess, I have a scientifically unwarranted affection for it, perhaps because of its beautifully symmetric molecules.

Despite my POV, I've tried to do a good job with the article and would like to help it eventually reach FA. Could you please look it over and make suggestions/criticisms, FA-related and otherwise? I'm sure that you'd find many things to correct or improve! Thanks muchly and hoping your departmental retreat was fun, Willow 22:28, 31 October 2006 (UTC)

He's commenting on the viewpoint of somebody else, I'll certainly have a look at this page. Thanks for the suggestion. TimVickers 23:06, 31 October 2006 (UTC)

Hi, Tim, Malaria is looking good! I had a question; I remember reading a rather provocative book some years ago, The Malaria Capers by Robert Desowitz. I don't remember it too well, but my impression was that he was rather severe on ill-considered Western interventions that had made malaria worse rather than better. Do you know the author, or have any opinion about his reliability?

I'm thinking of submitting Cyclol for Wikipedia:Scientific peer review soon, once I spruce up the section about modern cyclol chemistry. Did you get a chance to look at the article? Any suggestions would be much appreciated!  :) Willow 22:33, 7 November 2006 (UTC)

[edit] This month's winner is proteasome!

Proteasome
This month's MCB Collaboration of the Month article is proteasome.
Please help to improve this article to featured article status.
Last month's collaboration was adenosine triphosphate

ClockworkSoul 22:25, 1 November 2006 (UTC)

[edit] The E=mc² Barnstar

Thanks for the E=mc² Barnstar. I hope now that Flu is featured, you'll stick around and help with other flu and H5N1 articles. H5N1 is pretty good but you could make it better. Avian flu is terrible style-wise but then not all of can write as good as you do. WAS 4.250 21:18, 2 November 2006 (UTC)

[edit] Maintenance template on Enzyme

Hi TimVickers. I am back on Wikipedia, after completing my PhD on Enzyme Engineering. Thank you for inviting me to be added to the Template:Maintained list of the Enzyme page. I would like to be added to this list. Congratulations that Enzyme has become a featured article. TimBarrel 3 November 2006

[edit] MRSA

Hi, Tim ... I'm traveling, and don't have continuous internet access: would you be able to look at this message on my talk page? I'm not sure what Lucifer means by tagging and thought you would know. Thanks ! Sandy (Talk) 15:47, 8 November 2006 (UTC)

[edit] Cyclol as FAC

Hi, Tim, I just wanted to see how you were doing, and let you know that I rather impulsively put Cyclol up for FAC today. I know you felt unable to comment on it before and you may not feel able to support it now, and that's cool. But I couldn't forgo bothering you for insights into its other aspects, such as the writing, organization, images,... ;) I'm sure they would be helpful. Many, many thanks, Willow 21:36, 13 November 2006 (UTC)

[edit] Fujian flu

Hi. I just finished Fujian flu. I'm better at gathering the data than polishing it. Fujian flu is interesting as it is at the center of a power/politics struggle between WHO and China with the head of WHO just selected as a former China government health official and Chinese poultry vacinations looming in the background as a rumored cause of H5N1. WAS 4.250 22:40, 13 November 2006 (UTC)

Thanks for helping. I was unclear how much to say about the significance of the location itself. I am very unclear how much to say about the connection between the two types of flu. A good reason to have both types in one article instead of two articles and a disambig page is that talk of H5N1 recombining is to a degree talk about these two specific strains recombining (such has already occurred in pigs in China and a lab in the US; but in both cases producing nothing that infects humans at all so far as I know.) To complicate it, the H3N2 version has already mutated (drifted)into decendant strains given different names from newer isolates and China is denying the existence of genetic differences justifying singling out the H5N1 Fujian isolates as special while denying access to numerous isolates WHO wants. WAS 4.250 20:43, 15 November 2006 (UTC)

[edit] Malaria query

Hi, just noticed that on 29 October 06 you replaced the old malaria image of P. vivax in a cell with a false-colour electron micrograph image. You seem to be the main contributor to the article so I just wanted to say that as a layman knowledge-seeker(and malaria sufferer!) I found the old image more useful, and to ask if you could find a suitable place in the article to reinstate it. The new image doesn't mean anything to me - it's just a swirl of colour. With the old image I could clearly see the parasite in the cell, which was a lot more useful in visualising my new companions. The other pictures are a bit too small to see clearly. This is of course not meant to be a criticism of your work, just some user feedback! Cheers - Simon

[edit] Hemagglutinin

I just discovered Structure and Receptor Specificity of the Hemagglutinin from an H5N1 Influenza Virus. You may find it interesting. H5N1 genetic structure needs to be added to or altered a little based on it, but I find it difficult reading. WAS 4.250 00:29, 16 November 2006 (UTC)

[edit] Influenza. I only deleted some little words. And reshaped the whole paragraph.

But you took back all the changes I made without consideration. (in Influenza) Why Tim? You can't be bothered to see my whys? Hey, sorry to be a nag. Maybe you are a nice person after all. (easy to make war) My login name is pablo2garcia. 87.223.209.132 01:37, 16 November 2006 (UTC)

Hola, Pablo — encantada! :) I can assure you that Tim is nice, and very smart; you can be sure that he had a good reason for his reversions. Speaking for myself (who am not so smart), the disagreement may hinge on the choice of words; in English, we generally distinguish between the virus and the disease, i.e., we treat them as two separate things. More generally, please allow me to encourage you to log in under your user name, Pablo2garcia, to assume good faith and to continue contributing! Con affetto! :) Willow 03:35, 16 November 2006 (UTC)

[edit] Thanks, Tim!

Hi, Tim, I just realized that I forgot to do what I came here for last night, namely, to thank you for your help and insights on the Cyclol FAC. I'm really out of my depth when it comes to the philosophy of science, and never imagined that there would be much debate about the cyclol episode illustrating scientific method. I confess, I dread having to read those 20th century philosophers; they don't seem to have very lyrical terminology and I'm sure it will be tough going for my poor brain. :( Hopefully, your edits will resolve the objection. :) Willow 12:27, 16 November 2006 (UTC)

[edit] Anon uses a source I can't access

Please check this edit if you would. Similar edits have occured in the past. I can't access the sources being used, and its an anon, and I don't believe what is being said. So I reveted it. But I might be wrong. WAS 4.250 06:50, 17 November 2006 (UTC)

[edit] Cloning article

I agree in principle with your comment posted on the SCNT page. I would however suggest that A) The aforementioned article deals with both reproductive and therapeutic cloning, B) There is no reproductive cloning page on Wikipedia and C) Somatic cell nuclear transfer (SCNT) *is* both reproductive and therapeutic cloning as this is the core procedure in both cases, thus I believe it is pertinent to include a discussion of these forms of cloning from a personal perspective so I have re-included the webpage. Regards, George

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