Teicoplanin
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| Image:Teicoplanin.png | |
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Teicoplanin
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| Systematic (IUPAC) name | |
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| Identifiers | |
| CAS number | 61036-62-2 |
| ATC code | J01XA02 |
| PubChem | ? |
| Chemical data | |
| Formula | ? |
| Mol. weight | ? |
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| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
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| Pregnancy cat. |
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Teicoplanin is an antibiotic used in the prophylaxis and treatment of serious infections caused by Gram-positive bacteria. It is a glycopeptide antiobiotic extracted from Actinoplanes teichomyceticus, with a similar spectrum of activity to vancomycin. Teicoplanin is marketed by Aventis under the trade name Targocid®.
Oral teicoplanin has been demonstrated to be effective in the treatment of pseudomembranous colitis and Clostridium difficile-associated diarrhoea, with comparable efficacy to vancomycin. (de Lalla, 1992)
[edit] References
- de Lalla F, Nicolin R, Rinaldi E, Scarpellini P, Rigoli R, Manfrin V, Tramarin A (1992). "Prospective study of oral teicoplanin versus oral vancomycin for therapy of pseudomembranous colitis and Clostridium difficile-associated diarrhea.". Antimicrob Agents Chemother 36 (10): 2192-6. PMID 1444298.
- Gilpin M, Milner P (1997). Resisting changes -- Over the past 40 years the glycopeptide antibiotics have played a crucial role in treating bacterial infections. But how long can it continue ?. Royal Society of Chemistry. - includes picture of Teicoplanin's structure.
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| Glycopeptides (J01, and others) edit | ||
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Macrolides: Azithromycin, Clarithromycin, Dirithromycin, Erythromycin, Roxithromycin Others: Aztreonam, Monobactam, Teicoplanin, Vancomycin |
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