Thromboxane receptor
From Wikipedia, the free encyclopedia
The thromboxane receptor is a protein on the surface of cells in the endothelium of blood vessels and in the placenta which interacts with the eicosanoid lipid thromboxane. The gene responsible for the thromboxane receptor, TBXA2R is found on chromosome 19 and spans 15 kilobases. Thromboxane is an potent stimulator for platelet aggregation and clot formation and also plays a role in vascular tone. The thromboxane receptor is a member of the family of G protein-coupled receptors. Mutation of the receptor can lead to a bleeding disorder.
