Thiothixene
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| Image:Thiothixene.png | |
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Thiothixene
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| Systematic (IUPAC) name | |
| N,N-dimethyl-9- [3-(4-methylpiperazin-1-yl)propylidene]- thioxanthene-2-sulfonamide |
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| Identifiers | |
| CAS number | 5591-45-7 |
| ATC code | N05AF04 |
| PubChem | 5454 |
| DrugBank | none |
| Chemical data | |
| Formula | C23H29N3O2S2 |
| Mol. weight | 443.627 |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | Hepatic |
| Half life | 10-20 hours |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status |
? |
| Routes | oral, IM |
Thiothixene (sold as Navane®) is a thioxanthene drug used as a typical antipsychotic medication. It is a thioxanthene derivative and is the cis isomer of N,Ndimethyl- 9-[3-(4-methyl-1-piperazinyl)-propylidene] thioxanthene-2-sulfonamide.
Although widely used in the treatment of schizophrenia for several decades, thiothixene is seldom used today in favor of atypical antipsychotics such as olanzapine.
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