Precocious puberty

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**Precocious puberty**
*Classifications and external resources*
ICD-10	E 30.1, E 22.8
ICD-9	259.1
OMIM	176400
DiseasesDB	10519
MedlinePlus	001168
eMedicine	ped/1882

Precocious puberty means early puberty.

1 Types and causes
2 Clinical significance
3 Measures
4 Other notes
5 See also
6 References
7 External links

[edit] Types and causes

Early pubic hair, breast, or genital development may result from normal but early maturation or from several abnormal conditions. Early puberty which is normal in every way except age is termed idiopathic central precocious puberty. It may be partial or transient. Central puberty can also occur prematurely if the inhibitory system of the brain is damaged, or a hypothalamic hamartoma produces pulsatile gonadotropin-releasing hormone (GnRH). Secondary sexual development induced by sex steroids from other abnormal sources (gonadal or adrenal tumors, congenital adrenal hyperplasia, etc.) is referred to as peripheral precocious puberty or precocious pseudopuberty.

[edit] Clinical significance

Early sexual development deserves evaluation because it may:

induce early bone maturation and reduce eventual adult height,
cause significant social problems, or
indicate the presence of a tumor or other serious problem.

[edit] Measures

No single age limit reliably separates normal from abnormal processes, but the following age thresholds for evaluation will minimize the risk of missing a significant problem:

Pubic hair or genital enlargement in boys with onset before 9 years.
Breast development in boys before appearance of pubic hair and testicular enlargement.
Pubic hair before 8 or breast development in girls with onset before 7 years.
Vaginal bleeding in girls before 10 years.

Suggested causes: Environmental estrogens, sedentary lifestyle, and obesity

[edit] Other notes

Medical evaluation is sometimes necessary to recognize the few children with serious conditions from the majority who have entered puberty early but are still medically normal.

Children (esp. girls) who are obese are more likely to physically mature earlier.

Precocious puberty can make a child able to conceive when very young. Both sexes have become parents before age 10. The youngest mother on record is Lina Medina, who gave birth at the age of 5 years, 7 months and 21 days.