Parathyroid hormone receptor
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There are two known parathyroid hormone receptors in mammals termed PTH1R and PTH2R. These receptors are members of the 7 transmembrane G protein-coupled family of receptors. PTH1R is the classical PTH receptor, is expressed in high levels in bone and kidney and regulates calcium ion homeostasis through activation of adenylate cyclase and phospholipase C. PTH2R is expressed primarily in the central nervous system, pancreas, testis, and placenta.
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