Chinese Hamster Ovary cell
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Chinese Hamster Ovary cells (CHO cells) are a cell line derived from Chinese Hamster ovary cells. They are often used in biological and medical research. They were introduced in the 1960s and are used in a cultured monolayer in petri dishes. They require the amino acid proline in their culture medium; this property makes them ideal for genetics research. CHO cells are used in studies of genetics, toxicity screening, nutrition and gene expression particularly expression of recombinant proteins.
[edit] See also
[edit] Reference
Tjio J. H., Puck T. T., Genetics of somatic mammalian cells. II. chromosomal constitution of cells intissue culture. J. Exp. Med. 1958; 108: 259-271.
[edit] External links
- Phase contrast images of CHO cells
- Article from 1958 on culturing euploid cells
- http://www.biotech.ist.unige.it/cldb/cl721.html
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