Cefalotin
From Wikipedia, the free encyclopedia
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Cefalotin
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| Systematic (IUPAC) name | |
| (6R,7R)-3-(acetoxymethyl)- 8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia- 1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
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| Identifiers | |
| CAS number | 153-61-7 |
| ATC code | J01DB03 |
| PubChem | 6024 |
| DrugBank | APRD00859 |
| Chemical data | |
| Formula | C16H16N2O6S2 |
| Mol. weight | 396.44 g/mol |
| Pharmacokinetic data | |
| Bioavailability | n/a |
| Metabolism | hepatic |
| Half life | 0.5–1 hour |
| Excretion | renal |
| Therapeutic considerations | |
| Pregnancy cat. |
A (Aus) |
| Legal status | |
| Routes | IV |
Cefalotin (INN) (IPA: [kɛfəˈlotən, sɛfə-]) or cephalothin (USAN) (IPA: [kɛfəˈloθən, sɛfə-]) is a first-generation cephalosporin antibiotic. It was the first cephalosporin marketed and continues to be widely used. It is an intravenously-administered agent with a similar antimicrobial spectrum to cefazolin and the oral agent cefalexin. Cefalotin sodium is commonly marketed under the trade name Keflin (Lilly).
[edit] Clinical use
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Main article: Cephalosporin
[edit] See also
| Cephalosporin Antibiotics (J01D) edit | ||
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| First Generation: |
Cefacetrile, Cefadroxil, Cefalexin, Cephaloglycin, Cefalonium, Cefaloridine, Cefalotin, Cefapirin, Cefatrizine, Cefazaflur, Cefazedone, Cefazolin, Cefradine, Cefroxadine, Ceftezole |
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| Second Generation: |
Cefaclor, Cefamandole, Cefonicid, Ceforanide, Cefotiam, Cefprozil, Cefuroxime, Cefuzonam |
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| Third Generation: |
Cefcapene , Cefdaloxime, Cefdinir, Cefditoren, Cefetamet, Cefixime, Cefmenoxime, Cefodizime, Cefoperazone, Cefotaxime, Cefpimizole, Cefpiramide, Cefpodoxime, Cefsulodin, Ceftazidime, Cefteram, Ceftibuten, Ceftiofur, Ceftiolene, Ceftizoxime, Ceftriaxone, Latamoxef |
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| Fourth Generation: |
Cefclidine, Cefepime, Cefetecol Cefluprenam, Cefoselis, Cefozopran, Cefpirome, Cefquinome |
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