Bisoprolol
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Bisoprolol
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| Systematic (IUPAC) name | |
| 1-[4-[2-(1-methylethoxy)ethoxymethyl] phenoxy]-3-(1-methylethylamino)propan-2-ol |
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| Identifiers | |
| CAS number | 66722-44-9 |
| ATC code | C07AB07 |
| PubChem | 2405 |
| DrugBank | APRD00257 |
| Chemical data | |
| Formula | C18H31NO4 |
| Mol. weight | 325.443 g/mol |
| Pharmacokinetic data | |
| Bioavailability | >90% |
| Metabolism | Hepatic |
| Half life | 9-12hours |
| Excretion | Renal |
| Therapeutic considerations | |
| Pregnancy cat. | |
| Legal status |
℞ Prescription only |
| Routes | oral |
Bisoprolol is a drug belonging to the group of beta blockers, a class of drugs used primarily in cardiovascular diseases.
[edit] Indications
Bisoprolol can be used to treat cardiovascular diseases such as hypertension, coronary heart disease, arrhythmias, and treatment of myocardial infarction after the acute event. Patients with compensated congestive heart failure may be treated with Bisoprolol as a comedication (usually together with an ACE inhibitor, a diuretic and a digitalis-glycosid, if indicated). In patients with congestive heart failure, it reduces the need for and the consumption of oxygen of the heart muscle. It is very important to start with low doses, as bisoprolol reduces also the muscular power of the heart, which is an undesired effect in congestive heart failure.
The drug is also used to treat other conditions, including dysautonomia, anxiety and hyperthyroidism (overfunction of the thyroid gland).
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