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T辅助细胞 - Wikipedia

T辅助细胞

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细胞学T辅助细胞是一种T细胞白细胞的一种),它的表面有抗原感受器,可以约束由受感染的体细胞Class II MHC分子表现的抗原片段。

一旦贴近抗原,TH细胞就增殖和变异成活化TH细胞(activated TH)和记忆TH(memory TH)细胞。

  • 活化TH细胞分泌细胞因子、蛋白质或缩氨酸用来刺激其它的淋巴细胞;最通常是白介素(IL-2),这可以使得B细胞特化成plasma B cell。
  • 记忆TH细胞对第一次接触的抗原进行特化,这可以在被称为“二次免疫应答”中起作用。

很多TH细胞出现在CD4的细胞表面蛋白质上。这种亲和力使得TH细胞和靶细胞可以在抗原特化反应中紧密的贴在一起。带有CD4表面蛋白质的TH细胞称为CD4+ T细胞。

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