Inositol triphosphate receptor
From Wikipedia, the free encyclopedia
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inositol 1,4,5-triphosphate receptor, type 1
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| Identifiers | |
| Symbol(s) | ITPR1 |
| Entrez | 3708 |
| OMIM | 147265 |
| RefSeq | NM_002222 |
| UniProt | Q14643 |
| Other data | |
| Locus | Chr. 3 p26.1 |
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inositol 1,4,5-triphosphate receptor, type 2
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| Identifiers | |
| Symbol(s) | ITPR2 |
| Entrez | 3709 |
| OMIM | 600144 |
| RefSeq | NM_002223 |
| UniProt | Q14571 |
| Other data | |
| Locus | Chr. 12 p11.23 |
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inositol 1,4,5-triphosphate receptor, type 3
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| Identifiers | |
| Symbol(s) | ITPR3 |
| Entrez | 3710 |
| OMIM | 147267 |
| RefSeq | NM_002224 |
| UniProt | Q14573 |
| Other data | |
| Locus | Chr. 6 p21.31 |
Inositol trisphosphate receptor (IP3R) is a membrane glycoprotein complex acting as Ca2+ channel activated by inositol trisphosphate (IP3). It has a broad tissue distribution but is especially abundant in the cerebellum. Most of the IP3R's are found in the cell integrated into the endoplasmic reticulum. The IP3R complex is formed of four 313 kDa subunits. There are 3 isoforms and these can form homo- or hetero-oligomers.
See also:
- inositol
- inositol phosphate
- myo-inositol (inositol monophosphate).
- inositol triphosphate
- inositol pentakisphosphate
- inositol hexaphosphate
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This protein-related article is a stub. You can help Wikipedia by expanding it. |
| Lipid signaling |
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| Phospholipase | Phosphatidylinositol (4,5)-bisphosphate | Diacylglycerol | Inositol triphosphate | Inositol triphosphate receptor |
