Sinusoid (blood vessel)
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A sinusoid is a small blood vessel similar to a capillary but with a fenestrated endothelium.
Sinusoids are found in the liver, lymphoid tissue, endocrine organs, and hematopoietic organs such as the bone marrow and the spleen. Their highly permeable nature, which is due to larger inter-cellular clefts, fewer tight junctions, and fenestrated endothelial cells, allows small and medium-sized proteins such as albumin to enter and leave the blood stream. Some spaces are large enough for blood cells to pass. Liver sinusoids are equipped with Kupffer cells that can take up and destroy foreign material such as bacteria entering the sinusoids.
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